Combinatorial approaches have proven useful for rapid alloy fabrication and  optimization. A new method of producing controlled isothermal gradients using the Gleeble  Thermomechanical simulator has been developed, and demonstrated on the metastable β-Ti alloy  β-21S, achieving a thermal gradient of 525-700° C. This thermal gradient method has  subsequently been coupled with existing combinatorial methods of producing composition  gradients using the LENSTM additive manufacturing system, through the use of elemental  blended powders. This has been demonstrated with a binary Ti-(0-15) wt% Cr build, which has  subsequently been characterized with optical and electron microscopy, with special attention to  the precipitate of TiCr2 Laves phases. The TiCr2 phase has been explored for its high temperature  mechanical properties in a new oxidation resistant β-Ti alloy, which serves as a demonstration of  the new bicombinatorial methods developed as applied to a multicomponent alloy system.